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Funding This work was financially supported by the National Natural Science Foundation of China (grant number

It has an approved indication for HIV-associated lipodystrophy

8.1 Next-generation probiotics and recombinant forms of GLP-1 The concept of genetically modified probiotics is based on the creation of bacterial strains with predefined therapeutic functions that can synthesize biologically active molecules, such as hormones, cytokines, or peptides, directly within the gut