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Glutamine can serve as a precursor for aspartate through the concerted actions of glutaminase, yielding glutamate, followed by transfer of the nitrogen from glutamate to oxaloacetic acid (OAA) forming aspartate
J Neural Transm Suppl 72:3941 Hopp SC, Lin Y, Oakley D, Roe AD, DeVos SL, Hanlon D, Hyman BT (2018) The role of microglia in processing and spreading of bioactive tau seeds in Alzheimers disease
Molecular graphics and analyses were performed with the UCSF Chimera package and PyMOL Molecular Graphics System, Version 1.5.0.4 Schrodinger, LLC
Some of the detrimental effects of homocysteine are due to its binding to lysyl oxidase, an enzyme responsible for proper maturation of the extracellular matrix proteins collagen and elastin
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