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For people with problems absorbing the vitamin, pregnant women, and individuals suffering from mild deficiency, a 1000 mcg dose may be recommended

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Here are the specific energy and cognitive symptoms that targeted supplementation can address: Profound Fatigue and Post-Exertional Malaise (PEM): By unblocking the methylmalonyl-CoA pathway and feeding succinyl-CoA directly into the mitochondrial Krebs cycle, B12 restores the cellular capacity to generate ATP

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