There is no single correct amount more water simply spreads the same 12 mg of peptide across a larger volume, which makes small doses easier to measure accurately
But notably, the FDA made this statement in a release about bulk drug substances (ingredients used to make medicines) that it considers to pose potential significant safety risks, so KPVs lack of safety studies is a red flag in the FDAs eyes
Moreover, the resting heart rate variability (HRV) parameters also differed in ME/CFS patients, with a higher low frequency power of HRV (LFP) and a lower high frequency power of HRV (HFP)
Each amino acid contributes to the overall function
State of the clinical research For both compounds, the published clinical research in humans is limited: BPC-157 has not received approval as a medicine in any major regulatory jurisdiction (UK MHRA, EU EMA, US FDA)