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As previously reported, the transcellular Ca 2+ movement involves the participation of transient receptor potential vanilloid type 6 (TRPV6) and transient receptor potential vanilloid type 5 in the step across the brush border membrane from enterocytes, calbindin D 9k (CB D 9k ) as a ferry from one pole to the other pole of the cells and the plasma membrane Ca 2+ -ATPase (PMCA 1b ) and the Na + /Ca 2+ exchanger (NCX1) for cation extrusion[11]