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498 Studies on Tp IscR reveal that different homologues of IscR employ different ligand sets, despite what is likely the same function in surveilling the FeS status of the organism (Figure 17B)

Summary: B12 deficiency can make HbA1c results unreliable by disrupting red blood cell production and turnover, potentially distorting results in either direction

Scientists isolate the amino acid sequence from that natural protein and then synthesize it in laboratories to create a stable, consistent peptide for study

Peptide Sciences at least specifies in-house HPLC/MS but that's still self-reported data from the company that profits from positive results

The neurological consequences of untreated B12 deficiency can be serious and potentially permanent, including subacute combined degeneration of the spinal cord, which affects both sensory and motor pathways