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The most commonly reported adverse reactions were hypersensitivity reactions (e.g., rash, urticaria), edema-related reactions (e.g., arthralgia, extremity pain, peripheral edema, and carpal tunnel syndrome), hyperglycemia, and injection site reactions (injection site erythema, pruritus, pain, urticaria, irritation, swelling, and hemorrhage)

Its main characteristics include: Anti-oxidation : it neutralises free radicals, protecting skin cells from damage caused by UV radiation and oxidative stress

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Hyperthermia caused by laser irradiation increased cancer cell mortality to over 80% (Figure 1B), which eventually resulted in tumor inhibition (Figure 1C)