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[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed

It's the difference between a functional 1mg dose and a degraded 0.6mg dose that won't produce results

doi: 10.1083/jcb.124.6.949

The hypothesis underlaying this study is that the mere disciplinary, 'academic' culture of planning is per se not sufficient in unpacking the ontological and epistemological implications underpinning technoscientific-centrism

When the body has increased homocysteine, it can disrupt cognitive ability and affect mood leading to depressive symptoms [5]