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AFB 1 results in a significant and concentration-dependent increase in intracellular ROS production in BCMs because a main source of ROS can be mitochondrial respiratory chain uncoupling (133)

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Delescluse C, Ledirac N, Li R, Piechocki MP, Hines RN, Gidrol X, Rahmani R: Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells

10.4161/19490976.2014.990784 Gut Microbes 96 LawtonM.Ben-ShlomoY.MayM