Similar content being viewed by others 1 Introduction Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) analogue approved for the treatment of type 2 diabetes (T2D) as a once-weekly subcutaneous (s.c.) formulation and, more recently, as a once-daily oral formulation [1]
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Multiple cytokines and inflammatory factors participate in keloid formation, such as transforming growth factor 1(TGF-1), vascular endothelial growth factor (VEGF), interleukin (IL)-1, IL-6, and IL-8, as well as increased matrix metalloproteinases (MMP S ), which may promote fibroblast proliferation and migration, the inflammatory response, and collagen production 2,3,4
Its multifaceted benefits make it a formidable alternative to BPC 157 in peptide therapy
Preclinical models show activity at 24 weeks