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doi: 10.1016/j.molmed.2016.11.006

(2) it activates caspase-3, an enzyme inducing apoptosis

In the era of the cancer nanomedicine, many formulations, examples such as Abraxane, NanoTherm, and Combidexcomprising both organic and inorganic nanoparticleshave received clinical approval or are currently in clinical trials for solid tumors, but very few for glioblastoma (96, Table 5 )