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For instance, unimolecular doses of the dual-receptor agonist tirzepatide has effects that closely resemble dulaglutide, a pure GLP-1RA

257,258 Wnt signalling has a neuroprotective effect, and DKK1, as an antagonist of the canonical Wnt signalling pathway, is negatively correlated with changes in cognitive function

Figure 7 shows some hypothetical SDS-PAGE gels for GST pull-downs with these different domains

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