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As evidence, we can point not only to the fact that medical providers prescribe tesamorelin off-label to general populations for fat loss and muscle growth, but also to a 2006 study in which growth hormone replacement therapy significantly improved body composition in non-HIV patients with growth hormone deficiency.38 Specific side effects Some tesamorelin users experience flu-like symptoms such as fatigue, nausea, and headache

10.1038/nrd4461 115 NovikovA.FuY.HuangW.FreemanB.PatelR.van GinkelC.et al (2019)

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However, ongoing debate centers on whether the benefits of uric acid-lowering therapy stem from decreased uric acid levels or the inhibition of XO activity