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It is important not to exceed the recommended dose and to consider interactions with other medications the patient may be taking

Offering greater synthetic flexibility and similar protein resistance to PEG, PEtOx addresses immunogenicity concerns, though challenges in large-scale production and long-term in vivo studies persist

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Comorbid depression and diabetes worsen glycemic control, and certain antidepressants may inversely contribute to it

In males, ED is a prevalent complication, while females may experience sexual dysfunction, including decreased libido and arousal disorders