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This potent small molecule acts by inhibiting Nicotinamide Phosphoribosyltransferase (NAMPT), an enzyme crucial for the biosynthesis of Nicotinamide Adenine Dinucleotide (NAD+) from Nicotinamide

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The diagnosis was hyperammonemic encephalopathy due to valproic acid, which was treated with intravenous L-carnitine

This review summarizes each step of glutamine metabolism in cancer cells and highlights opportunities for clinical intervention