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495 In addition, BO decreases ROS and MDA content and the atherosclerosis index in tissues, while increasing antioxidant enzyme activity, including SOD, GPX and catalase, 495 suggesting that mixed oils with a low n 6/ n 3 PUFA ratio could be effective in preventing and managing cardiovascular diseases

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This mechanism is plausible biochemically, and some human trials support it but with important limitations

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