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10.1096/fj.09-149997 58 LimongiD.BaldelliS.ChecconiP.MarcocciM

These findings suggest that GBM cells have increased dependence on DHHC9-mediated GLUT1 S-palmitoylation, unlike normal astrocytes which primarily depend on other mechanisms to maintain their glycolysis, highlighting that DHHC9 could be a potential target for cancer cell-specific inhibition of glycolysis

siRNA: novel therapeutics from functional genomics

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While NapA possesses pro-inflammatory and iron storage capabilities, its potential role in ferroptosis in GC and related human malignancies has not been extensively studied, thus warranting further consideration and exploration