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"On the reaction mechanism of yeast glutathione reductase"

had demonstrated that dihydroartemisinin exhibited anti-cancer efficacy in the treatment of SGC7901/DDP cells, and significantly enhanced the levels of autophagy-related proteins such as Beclin-1 and LC3II by inhibiting the PI3K/Akt/mTOR signaling pathway while concurrently downregulated P-gp, thereby increasing sensitivity to cisplatin (112)

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Proc Natl Acad Sci U S A 111(11):40014006

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