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Specifically, we observed an upregulation of Glp1r (encoding glucagon-like peptide-1 receptor, GLP-1R), Htr4 (encoding 5-HT4 receptor), and Ntsr1 (encoding neurotensin receptor 1, NTR1)

It is important to note that off-label prescribing of combination weight loss medications may occur in some specialist settings, but this should only be undertaken by experienced clinicians who can provide close monitoring and have thoroughly assessed the individual patient's risk-benefit profile

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