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[21] The Leiden University study found that as much as 3040% of inhaled THC was not absorbed by the lungs but simply exhaled

They could be a potential gateway to new smokers, particularly among teenagers and in emerging/foreign markets, according to behavioural scientists at The University of Texas MD Anderson Cancer Centre

Subjects were then randomized by a block size of 3 to one of the IP sequences, (sequence[subjects]): (ABECD [3], BCADE [3], CDBEA [4], DECAB [3], EADBC [3], DCEBA [3], EDACB [4], AEBDC [3], BACED [3], and CBDAE [4]) to use one IP in each session

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Other references Barrington-Trimis JL, Urman R, Berhane K, et al