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Exosome cargos offer prognostic insights for various diseases, including cardiovascular, renal, neurodegenerative, and metabolic disorders, as well as cancer

This work was partly supported by Grants-in-Aid from the Japan Society for the Promotion of Society (17K16958 to K.S., 17H04349 to T.N.)

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Potential Benefits Works through amylin receptors rather than GLP-1, offering an alternative pathway for patients who may not respond optimally to GLP-1 medications alone

As reported in a randomized controlled trial, two patients with advanced liver disease, out of 69 patients in the simvastatin group, receiving simvastatin 40 mg/day experienced rhabdomyolysis, with no such sign found in the placebo group (Abraldes et al., 2016)