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There are strong links between some of these carcinogens and various types of smoking-induced cancers

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Gender differences in usage patterns have also been reported: males generally show higher rates of lifetime, current, and dual e-cigarette use compared with females ( Table 1 Predictive and protective factors for the use of the e-cigarette in young people

In 1929, the stock market crashed and triggered the Great Depression, a major economic downturn that led to severe rates of unemployment and business failures