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Statements Author contributions CL and GK participated in the design, writing, and final corrections of the manuscript

TB-500 specifically corresponds to the 17-amino-acid active site within T4 responsible for actin binding and cell migration signaling

Research indicates that GHK-Cu can alter the activity of more than 4,000 human genes, shifting patterns away from inflammation and tissue degeneration toward profiles associated with repair, regeneration, and homeostasis [1]

J.KubotaH.TanguayR

The clinical sequela of these changes is the development of sharp shock-like or burning pain, characterized by dysesthesia and allodynia, and loss of cutaneous sensation and autonomic function