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Acute or chronic renal impairment may develop with lupus nephritis, leading to acute or end-stage kidney failure

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2018 Jan Anup Sharma, Patricia Gerbarg, Teodoro Bottiglieri, Lila Massoumi, Linda L Carpenter, Helen Lavretsky, Philip R Muskin, Richard P Brown, David Mischoulon

10.1056/NEJM198409203111207 N

Results Endogenous MOTS-c levels increase upon exercise in humans To determine if endogenous MOTS-c responds to physical exertion, and thus may be involved in driving adaptation to enhance physical capacity, we collected skeletal muscle and plasma from sedentary healthy young male volunteers (24.5 3.7 years old and BMI 24.1 2.1) that exercised on a stationary bicycle (Fig