FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data
It functions by constricting the blood vessels in the brain, reducing inflammation, and limiting the release of certain substances that trigger pain, nausea, and other symptoms associated with these conditions
Rude RK, Singer FR, Gruber HE
Wenn jemand jetzt parallel eine verbotene oder geheimnisvolle Substanz nimmt, daran glaubt, seine Sehne wieder mehr belastet, sich mehr zutraut und pltzlich konsequenter trainiert, ist die Geschichte halt schnell erzhlt: Das Peptid hat mich geheilt. Vielleicht
Labeling tumor-homing peptides on the surface of exosomes loaded with therapeutics can reduce major adverse side effects in cancer therapy 34
