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For example, one study found that platelets from individuals with autoimmune thrombocytopenia expressed evidence of elevated oxidative stress, which is countered by antioxidants (Kamhieh-Milz 2012)

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Compared with earlier studies, the present analysis captures long-term reporting trends from 2004 to 2025 across eight PD-1/PD-L1 inhibitors and applies four internationally recognized disproportionality methods (ROR, PRR, IC, and EBGM)