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A practical view of fine-mapping and gene prioritization in the post-genome-wide association era

More often, it struggles because teams have to make huge decisions with models that may not be predictive enough of what will happen in humans

Resistant cells showed coordinated activation of survival pathways and reduced expression of several CRL4CRBN components, indicating both CRBN-dependent and -independent escape routes

Our results showed that DEX increased the translocation of GRs to mitochondria, and this effect was accompanied by decreases in the expression of mitochondrially encoded cytochrome c oxidase 1 (MT-CO1) and mitochondrially encoded cytochrome c oxidase 3 (MT-CO3) and increases in the expression of NOD-like receptor thermal protein domainassociated protein 3 (NLRP3), caspase-1, and Gasdermin D (GSDMD)

Major and minor depression in later life: a study of prevalence and risk factors