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No other significant associations were found between metabolites measured at 3 months and symptoms measured at 3 months

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Signal 1 (also known as the priming signal) is mediated by the transcriptional expression of pro-IL1B (interleukin 1 beta) and pro-CASP11 through the activation of the NFKB/NF-B (nuclear factor kappa B) pathway [118]

NTZ-200 exhibited a better effect than NTZ-100 and resembles the effect of both NAC and 4-PBA (Figure 3A)