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(b) the paracellular route used by ions, water and larger hydrophilic compounds from ~400600 Da up to 1020 kDa and that cannot cross transcellularly [regulated by the tight junction (TJ) proteins]

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Studies on cultured dermal papilla cells, which are critical for regulating the hair growth cycle, investigate the peptide's influence on cell proliferation and the expression of growth factors like VEGF