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The quenching reaction involves physical contact between the quencher and an excited indole ring, and can be kinetically described in terms of a collisional and a static component (Eftink and Ghiron, 1976)

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Another effect of Epithalon on the skin fibroblasts during aging is the reduction of the enzyme caspase-3 activity, which is in the pathway of apoptosis or programmed cell death

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