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When the mitochondrial excessive accumulation of ROS damages the structure of luteal cells and the placental trophoblasts, reduces ATP production, the steroid metabolism is consequently disturbed

Life Sci 198:1824 Lima IFP, Nobrega DF, Cericato GO, Ziegelmann PK, Paranhos LR (2019) Prevalence of dental fluorosis in regions supplied with non-fluoridated water in the Brazilian territory: a systematic review and meta-analysis

The window for meaningful intervention is widest at this early stage

Topaloglu R, Gultekingil A, Gulhan B, Ozaltin F, Demir H, Ciftci T, Demir N, Temucin CM, Yuce A, Akhan O (2020) Cystinosis beyond kidneys: gastrointestinal system and muscle involvement

Ling, M.B