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Internet sellers and research only vendors do not provide the same safeguards

doi:10.7860/JCDR/2016/22027.8671 [5] Taska K, Gietka-Czernel M, Glinicki P, Kozakowski J

Signs you're using too high a concentration include persistent redness, increased sensitivity to other products, dryness that doesn't respond to moisturizer, and skin that looks worse rather than better over time

The duration of therapy varies depending on the indication and patient response, with some protocols recommending treatment for several weeks to months

What does exist falls into a few categories, none of which meets the bar that the word clinical ordinarily sets: Historical and patent-era work