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Grading of recommendations Recommendations are graded according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.21 Whether a recommendation is strong or conditional will depend on considerations such as certainty in estimated effects of an intervention, including magnitude, as well as estimates of how patients value and prioritize outcomes, variability of these estimates, and wise use of resources

That also undermines the idea that marijuana impairs cognition

Some vapor is exhaled, and nicotine delivery from vaping is less efficient than burning tobacco

Why does that happen