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doi: 10.1093/oxfordjournals.molbev.a026061 98 FengS.Enosi TuipulotuD.PandeyA.JingW.ShenC.NgoC.et al

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We dont know whether the participants were B12 deficient and were being made B12 replete, or whether they were B12 replete to start with and this was additional B12, which would be important to know if you did think that this were an effective therapy. Dr Whittle said there were some effective pharmacotherapies for fibromyalgia such as duloxetine or pregabalin

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The frequency of monitoring is determined by the prescribing physician based on the protocol and individual response