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For arthritis specifically, semaglutide has evidence from the STEP-9 knee osteoarthritis trial and studies on rheumatoid arthritis joint outcomes, while tirzepatide has shown roughly a 33% reduction in hsCRP and an 18% reduction in IL-6 (key inflammation markers) in meta-analyses

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This process should include a comprehensive review of the manufacturers quality assurance practices, examination of certificates of analysis (COAs), verification of sterility and endotoxin testing, and confirmation of peptide identity, purity, and potency through validated analytical methods