When administered either orally, intraperitoneally, or intracerebroventricularly at various doses, Dihexa-treated rats showed significantly improved performance in both acquisition trials and probe trials measuring spatial memory retention
10.1038/s41587-021-00950-3
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Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, 587-602
The duration and intensity of exercise influence serotonin metabolism in distinct brain regions: acute swimming (1 h) increases 5-HT and 5-HIAA levels specifically in the brainstem, while prolonged swimming (4 weeks) enhances serotonin turnover in the cerebral cortex, with effects persisting for up to a week post-exercise