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Phase 2 dose-ranging trials followed in 20042006, and the pivotal Phase 3 trials (studies LIPO-010-05 and LIPO-010-06) ran from 2006 to 2009 , forming the efficacy basis for the November 2010 FDA approval

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Gressmann H, Linz B, Ghai R, Pleissner K-P, Schlapbach R, Yamaoka Y, Kraft C, Suerbaum S, Meyer TF, Achtman M (2005) Gain and loss of multiple genes during the evolution of Helicobacter pylori

CJC-1295 without DAC , often called Modified GRF (1-29) , is shorter acting and relies more heavily on broader GHRH analog and sermorelin-adjacent evidence

10.1136/jitc-2022-005940 [DOI] [PMC free article] [PubMed] [Google Scholar] Kawaguchi Y., Sakamoto Y., Ito D., Ito K., Arita J., Akamatsu N., et al