Am J Hum Genet 85:493502 Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabon MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM (2016) Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice
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The disease is most common in men from middle age onwards - an onset before the age of 40 is rare
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Pairing Connecticut Broadleaf Given the above-mentioned characteristics, Connecticut Broadleaf wrappers pair exceptionally well with complex beverages like whiskey, espresso, or rum