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While oral glutathione bioavailability has historically been debated, liposomal and acetylated forms improve uptake

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Collectively, the Nrf2/HO-1 and GPX4 pathways constitute well-established molecular targets for antioxidant-mediated bone protection, with products such as punicalagin, naringenin, and geniposide demonstrating consistent efficacy across experimental platforms

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However, the role of aKG as a protective factor against systemic inflammation associated with long COVID cannot be disregarded [67]