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Hypothesising that decreased macrophage viability in an oxidative environment could be a contributing factor to the pathophysiology of CD, we found that monocyte-derived macrophages from individuals with active CD (but not those in clinical disease remission) have increased sensitivity to cell death induced by H 2 O 2

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has shown the direct double-stranded RNA-specific binding capacity of Drosophila HSC70-4 ( Forward-looking perspectives Since its discovery, the heat shock protein superfamily has attracted immense interest, fueling many studies revealing its ubiquitous role and powerful therapeutic potential

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