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Based on these findings, they proposed that the pathological formation of MSU in humans may follow an AMSU precursornonclassical crystallization pathway ( As a relatively stable and low-inflammatory precursor phase, AMSU tends to induce heterogeneous nucleation and deposition on damaged articular cartilage surfaces, synovial connective tissue, or cell-derived vesicles at various biological interfaces, and may participate in the uric acid crystallization kinetics process within a certain timescale (1014)

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The glucose transporter 4, or GLUT4, is the primary transporter that facilitates glucose uptake into muscles and adipose tissues in response to insulin (Wang, Wang, et al

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