Compared to Oral administration, whereby under 10% actually enters the blood stream, Oro-buccal administration by Oral Dispersible Film(ODF) leads to over 80% absorption directly into the systemic circulation
Xue H, Sufit AJ, Wischmeyer PE (2011) Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models
ORiordan W, McManus A, Teras J, Poromanski I, Cruz-Saldariagga M, Quintas M, Lawrence L, Liang S, Cammarata S, PROCEED Study Group
If side effects are stronger than expected (which can happen if your sublingual bioavailability is on the higher end), decrease by 0.5 to 1 mg daily
Furthermore, we found tamoxifen as undeclared API in seven samples, together with chlorodehydro-methyltestosterone, stanozolol, anastrozole, oxandrolone, ligandrol, or cardarine (Table 2)