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Its activity can be reduced in physiological conditions, it is susceptible to proteolytic degradation, and it can exhibit cytotoxicity at high concentrations

Cascone T, William Jr WN, Weissferdt A, Leung CH, Federico L, Haymaker C, Bernatchez C, Fossella FV, Mott FE, Papadimitrakopoulou VA, Byers LA, Lam VK, Godoy MC, Lee JJ, Vaporciyan A, Givvons DL, Swisher SG , Heymach JV, Sepesi B

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