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In this case, the company did not provide sufficient evidence of a benefit that outweighs the risk, particularly given evidence that adults who smoke generally do not stop or significantly curtail consumption of cigarettes when using this product. Tobacco products that receive an MDO from the FDA may not be introduced or delivered for introduction into interstate commerce and must be removed from the market

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If you do not smoke tobacco but rather ingest it, there are also adverse side effects

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age of onset of vaping, cigarette smoking, psychological distress) and information on motivation leading up to onset (and discontinuation) of vaping, would have provided additional context regarding the role of vaping in daily cigarette consumption