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While macrophages can potentially eradicate amastigotes through appropriate activation, Leishmania employs diverse strategies to thwart this activation and redirect macrophages toward an M2 phenotype, facilitating its survival and replication

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Many individuals report feeling less exhausted during exercise, faster recovery times, and greater endurance

Importantly, it revealed inter-patient variability in response to chimeric antigen receptor (CAR)-T-cell therapy, capturing both effective tumor eradication and excessive cytokine release patterns that mirror clinical immune-related toxicities