Why combine them
10.1523/JNEUROSCI.1365-09.2009 Summary Keywords NMDA receptors, GluN2B, GSH metabolism, gamma-Glu-Glu, partial effect Citation Sebih F, Mokrane N, Fontanel P, Kayatekin M, Kaabeche M, Guiramand J, Cohen-Solal C, Cens T, Rousset M, Charnet P, De Jsus Ferreira M-C, Thibaud J-B, Mnard C, Cantel S, Rolland V, Vignes M and Roussel J (2022) The Glutathione Metabolite -Glutamyl-Glutamate Partially Activates Glutamate NMDA Receptors in Central Neurons With Higher Efficacy for GluN2B-Containing Receptors
Migraine is a multifactorial disorder closely related to oxidative stress and neurogenic inflammation
Topical application has the following advantages: It doesn't change the overall color of the skin
For those just starting, an initial dose of 500 mg or 1000 mg is often suggested to gauge the bodys response