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The drug-response interactions model has many other limitations regarding biphasic dose response

Interestingly, the application of low-magnitude compressive stress (0.03 kPa) on weakly adhesive MDA-MB-231 breast cancer cells decreases their motility, highlighting the critical role of cell-matrix interactions in stress-dependent cell responses [122]

Relaxation induced by each concentration of BPC 157 was measured after the response reached steady-state, and the value was expressed as a percentage of the initial vasoconstrictor-induced tone

On the basis of CVMI, all subjects were divided into six groups based on whether the subjects remained in same CVMI stage or transitioned to the next CVMI stage