Misunderstanding 3: Positive Cell Studies Mean FDA-Approved Efficacy Correction: In vitro cell studies and animal studies cannot be considered FDA approval of cosmetic efficacy
Read review Dihexa for Endometriosis Brain Fog The November 2025 Lancet O&G/WH 'overlooked symptom' commentary from Edinburgh EXPPECT, the April 2025 Horn FACT-Cog 1,239-patient survey (~80% perceived cognitive impairment), the March 2025 NICE TA1057 Ryeqo approval (first daily pill on NHS), the April 2024 NICE NG73 update, the April 2026 renewed Womens Health Strategy with 117 action points, the 2023 Greaves CNS-wide glial activation mouse model, the BDNF/TrkB central-sensitisation directionality paradox, and the ~1.5 million UK women affected
The antiasthmatic effect of ACA was suggested by its ability to work on immunological and inflammatory pathways (Seo et al., 2013)
[DOI] [PubMed] [Google Scholar] 9.Royea J., Hamel E
(4) W Larbig, W D Gerber, M Kluck, and G A Schoenenberger (1984) Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes