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Most cases involve some combination of both components

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When evaluating side effects, the following frequencies are used as a basis: Very common: more than 1 in 10 people Common: less than 1 in 10, but more than 1 in 100 patients Uncommon: less than 1 in 100, but more than 1 in 1000 patients Rare: less than 1 in 1,000 but more than 1 in 10,000 patients Very rare: less than 1 in 10,000 patients treated, or unknown