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An open-label, investigator-initiated, single-center, prospective, pilot clinical study to evaluate the efficacy of a skin whitening serum applied twice daily combined with a spot-preventing SPF50+ sunscreen in healthy female subjects with melasma hyperpigmentation

Patient experiences vary, but a general arc tends to look like this: Some patients report mild detoxification symptoms in the first one or two sessions, sometimes called a Herxheimer-like response, as toxins begin to mobilize

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This could also contribute to pleiotropic health

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